There are two phases in the curriculum; the Medical Sciences Phase (Phase 1) which is the first two years of study, and the Clinical Phase (Phase 2) which is carried out in three subsequent years of study. Each phase is strategised to have four blocks and the modules/postings are repackaged and rearranged as follows.

The Medical Sciences Phase, also known as the Pre-clinical Phase, consists of four blocks which are Block 1 (Foundation in Medical Sciences), block 2 (Introduction to Behavioural Science, Clinical, and Community Medicine), block 3 (System-Based Medical Sciences I), and block 4 (System-Based Medical Sciences II).

The Clinical Phase also comprises 4 Blocks which spans over 3 years. These blocks are designated as Block 5 (Junior Clerkship), block 6 (Specialty Clerkship I), block 7 (Specialty Clerkship II), and Block 8 (Senior Clerkship). For the contents of each block, please refer to the modules below. Throughout the 5 years of study, subjects on soft skills development are also incorporated such as communication skills, behavioural science, team building, critical thinking, problem-solving, leadership, and management.

The SEGi MBBS programme is internationally established and recognised by the various medical councils and regulatory bodies around the world including Malaysia, Thailand, Pakistan, Qatar and Maldives.